Exposure to difenoconazole induces reproductive toxicity in zebrafish ... Uses of Difenoconazole: this chemical is triazole fungicides. Difenoconazole plus Metalaxyl - HerbiGuide The aim of the present study was therefore to evaluate the toxicity of abamectin, difenoconazole and their mixture to the tropical fish Danio rerio. This was manifest as gross distension of the bile duct, increased numbers of lining cells and inflammation of the duct. In this study, zebrafish embryos were exposed to DIF (0, 0.3, 0.6 and 1.2 mg … No toxicologically significant effects were seen in repeat dose dog studies. International Conference on Environmental Research and Technology ... The acute oral toxicity Lethal Dose 50% (LD 50) was 1,453 milligrams per kilogram (mg/kg) (Toxicity Category III). PDF SAFETY DATA SHEET - Syngenta H302: Harmful if swallowed [Warning Acute toxicity, oral] H361d ***: Suspected of damaging the unborn child [Warning Reproductive toxicity] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long . Difenoconazole; Pesticide Tolerances, 32482-32488 [2017-14105] On the other hand, isobutanol is highly flammable, but the amount of isobutanol EC with IL 5 was 25 wt%, which was much lower than that of toxic aromatic compounds of commercial difenoconazole ECs. DOAJ is a community-curated online directory that indexes and provides access to high quality, open access, peer-reviewed journals. in the Environmental Hazards section. Facebook Twitter Share. The limit ofquantitation . Common Name of A.I : Difenoconazole 150 g/l + Propiconazole 150 g/l Chemical Name : Difenoconazole Cis,trans-3-chloro-4-[4-methyl-2- (1H-1,2,4 . It is also risk of serious damage to the eyes. The toxicity database for difenoconazole is complete. phenyl]difenoconazole or [14 C-triazole]difenoconazole at 0.5 mg/kg bw, 13-22% of the administered dose was excreted in the urine and 81-87% in the faeces. Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior Author: Xiangguang Chen, Junyue Zheng, Jie Zhang, Manman Duan, Hao Xu, Wentian Zhao, Yang Yang, Chengju Wang, Yong Xu Source: Science of the total environment 2022 pp. It was of low acute toxicity dermally and through inhalation exposure. (Acute toxicity, dermal, category 3)\nToxic if swallowed. difenoconazole | CAS#:119446-68-3 | Chemsrc OTHER TOXICITY: May cause damage to organs (liver, kidneys and thyroid effects) at high doses. Harmful if swallowed. In Costa Rica, agriculture is one of the most important economic activities. It is slightly volatile, persistent in soil and in the aquatic environment. The Meeting concluded that difenoconazole is unlikely to be genotoxic. Although potentially a mobile molecule it is unlikely to leach due to its low aqueous solubility. ii. ECOLOGICAL INFORMATION ELIMINATION INFORMATION (PERSISTENCE AND DEGRADABILITY) . Tebuconazole | C16H22ClN3O - PubChem A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2-chloro-4-(4-chlorophenoxy)phenyl and 1,2,4-triazol-1-ylmethyl groups. Difenoconazole exposure induced plant leaf cells to generate more ROS (O2•− and H2O2) and MDA, which resulted in a decreased chlorophyll content and then inhibited leaf photosynthesis. Early Toxic Effects in a Central American Native Fish ( Parachromis ... Yet despite this, the PMRA continues to register difenoconazole as an active ingredient in many pest control products. PDF Safety Data Sheet Some previous studies demonstrated the toxic effects of DIF on non-target animals, however, there were still some gaps in the knowledge of the potential hazards of DIF to mammals and human health. ChEBI CHEBI:81760 12. Azoxystrobin is toxic to freshwater and estuarine/marine fish and aquatic invertebrates. SECTION C FULL REPORT OF INVESTIGATIONS MADE WITH RESPECT TO THE SAFETY OF THE PESTICIDE CHEMICAL Difenoconazole Technical Difenoconazole is classified as a Toxicity Category Ill pesticide with the signal word "Caution". PDF Difenoconazole -MATERIAL SAFETY DATA SHEET - T3DB There are no clear signs of neurotoxicity following acute, subchronic, or chronic exposure in multiple species in the difenoconazole Start Printed Page 51737 study database. Difenoconazole supplier | CasNO.119446-68-3 - LookChem PDF US EPA - Difenoconazole Tolerance Petition - October 2006 There are signs of . Difenoconazole is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death. Efficacy of Difenoconazole Emulsifiable Concentrate with Ionic Liquids ... Section 408(b)(2)(D)(v) of FFDCA requires that, when considering whether to establish, modify, or revoke a tolerance, the Agency consider ``available information'' concerning the cumulative effects of a particular pesticide's residues and ``other substances that have a common mechanism of toxicity.'' Difenoconazole is a member of the conazole . Difenoconazole SAFETY DATA SHEET 2.3Causes serious eye irritaiton. It is moderately toxic to humans, mammals, birds and most aquatic organisms. Although the values of difenoconazole were lower than those of the commercial difenoconazole ECs, toxic organic solvent was decreased. In PRD2015-29, the PMRA acknowledges evidence of potential risk for aquatic organisms Very toxic to aquatic life with long lasting effects. Formulation and dosage of Difenoconazole: Usage: 10%WDG: 15%WDG: 20%WDG: 30%WDG: 37%WDG: 60%WDG: pear: scab: dilution rate: 6000-7000. dilution rate: 9000-10000. dilution rate: 12000-14000 . 112-120. Difenoconazole possesses low acute toxicity by the oral, dermal and inhalation routes of exposure. Toxicity of Difenoconazole and Tebuconazole in Allium cepa Difenoconazole exhibits some evidence of neurotoxicity in the database, but the effects are transient or occur at doses exceeding the limit dose. High quality 25%EC Difenoconazole Fungicide pesticide agrochimique from China, China's leading CAS 119446 68 3 difenoconazole fungicide product, with strict quality control 25%EC difenoconazole fungicide factories, producing high quality Difenoconazole Herbal Fungicide For Plants products. Difenoconazole: Kidney and liver effects at high doses (>5000 ppm; rats); Eye .
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